Ligand Exchange HPLC Column
Ligand exchange columns are use for the analysis of carbohydrates, alcohols and organic acids. However, most columns in the market are produced from low crosslinked resin and limited the speed of separations because of back pressure. BioChrom
developed ligand exchange HPLC column, Hydrocell SCX 100 by sulfonating the high crosslinked polystyrene-divinylbenzene beads with average particle size 5 µm and pore size 100 A.
The resin can be changed its selectivity by ligand exchange interaction with metal ion such as sodium, calcium and lead. The selection of molecular weight range of analysis can also be controlled by changing crosslinked percentage of resin. Pharmacopeia methods
specify the type of HPLC column which should be used. Hydrocell SCX 100 column comply with USP definitions of Media Type L17.